Plain-language brief
What this opportunity funds
The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models studying infectious diseases and testing of medical interventions. The NIH and FDA have recently issued guidance and established initiatives for enhancing use of New Approach Methodologies (NAMs) in research and product development. This includes in vitro systems that allow scientists to model human disease and capture human variability and patient-specific characteristics that will accelerate safer treatments for patients while reducing costs and sparing use of laboratory animals. To meet this need, the Centers will refine well validated human tissue models studying infectious diseases to a level consistent with regulatory qualifications that will promote their adoption for use by product developers, supporting regulatory acceptance.
Eligibility at a glance
- Eligible applicants
- For profit organizations other than small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification), Independent school districts, Small businesses, Private institutions of higher education, County governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Native American tribal organizations (other than Federally recognized tribal governments), Native American tribal governments (Federally recognized), Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, Special district governments, City or township governments
- Eligible locations
- Eligible applicants across the United States
- Eligible activities
- Health
- Matching requirement
- Not specified
- Registration
- SAM.gov, Grants.gov
Application process
- Read the complete official notice and confirm every eligibility rule.
- Complete required registrations early; federal registrations can take time.
- Build the budget, work plan, evidence, and attachments requested by the sponsor.
- Submit through the official portal and retain the confirmation.
Change history
No material changes have been recorded since this opportunity entered the hub.