Plain-language brief
What this opportunity funds
The purpose of this Notice of Funding Opportunity (NOFO) is to support SenNet Discovery and Validation Centers (SenNet DVCs) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). Building on Stage 1 resources, DVCs will define, refine, and validate tissue- and disease-relevant cellular senescence signatures (“senotypes”) and associated biomarkers, and will investigate their functional consequences in human health and disease. DVCs are expected to generate and contribute high-quality molecular, cellular, and spatial datasets (including relevant metadata and documentation) and to use complementary experimental systems, as appropriate, to validate senotypes/biomarkers and characterize responses to senescence-associated perturbations or senotherapeutic approaches. DVC applications should also propose goals and aims for SenNet consortium-wide organizational and outreach activities (SenNet OOC functions).
Eligibility at a glance
- Eligible applicants
- Independent school districts, Public housing authorities/Indian housing authorities, State governments, Small businesses, Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Native American tribal organizations (other than Federally recognized tribal governments), County governments, Native American tribal governments (Federally recognized), City or township governments, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses, Special district governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), Private institutions of higher education
- Eligible locations
- Eligible applicants across the United States
- Eligible activities
- Health
- Matching requirement
- Not specified
- Registration
- SAM.gov, Grants.gov
Application process
- Read the complete official notice and confirm every eligibility rule.
- Complete required registrations early; federal registrations can take time.
- Build the budget, work plan, evidence, and attachments requested by the sponsor.
- Submit through the official portal and retain the confirmation.
Change history
No material changes have been recorded since this opportunity entered the hub.