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FORECASTEDNationwide

Elucidation and Validation of the role of Transporters in the Placenta, Lactating Mammary Gland, Developing Gut, and Blood Brain Barrier

The Eunice Kennedy Shriver National Institute of Child Health and Human Development seeks to advance its mission of supporting maternal, fetal, and child health by continuing to enhance the understanding of maternal, fetal, and child exposure to nutrients, metabolites, medications, supplem

Plain-language brief

What this opportunity funds

The Eunice Kennedy Shriver National Institute of Child Health and Human Development seeks to advance its mission of supporting maternal, fetal, and child health by continuing to enhance the understanding of maternal, fetal, and child exposure to nutrients, metabolites, medications, supplements, microbiome-derived products, and environmental chemicals. This will be done by supporting a second phase of the Transporter Elucidation Network (TEN). This phase of the TEN will establish perinatal multi-barrier transport network frameworks to clarify how transporters and local biotransformation regulate these processes. Building on prior organ-focused models, methods, and datasets, this initiative will develop standards, resources, models, and prototype multi-compartment approaches spanning maternal gut, placenta, lactating mammary epithelium, infant gut, and infant blood-brain barrier. The initiative is expected to support a mechanistic understanding of transporter function, polarity, kinetics, and transformation capacity relevant to pregnancy, lactation, infant nutrition, pediatric pharmacology, and neurodevelopment. By emphasizing multi-barrier perinatal transporter frameworks this phase of the TEN will provide community resources for future integrated studies of perinatal exposure, risk, and intervention across interlinked maternal, fetal, and infant systems. It will also strengthen coordination among investigators, accelerate dissemination of tools, and advance human-based, developmentally relevant transporter research and workforce development. The grant authority for this is 42 U.S.C. § 241

Eligibility at a glance

Eligible applicants
County governments, Native American tribal governments (Federally recognized), Independent school districts, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Native American tribal organizations (other than Federally recognized tribal governments), Special district governments, Small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification), Public housing authorities/Indian housing authorities, For profit organizations other than small businesses, Public and State controlled institutions of higher education, City or township governments, Private institutions of higher education, State governments, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Eligible locations
Eligible applicants across the United States
Eligible activities
Health
Matching requirement
Not specified
Registration
SAM.gov, Grants.gov

Application process

  1. Read the complete official notice and confirm every eligibility rule.
  2. Complete required registrations early; federal registrations can take time.
  3. Build the budget, work plan, evidence, and attachments requested by the sponsor.
  4. Submit through the official portal and retain the confirmation.

Change history

No material changes have been recorded since this opportunity entered the hub.

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