Plain-language brief
What this opportunity funds
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies for cancer research or clinical care. This NOFO solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still requires further development, enhancements, optimizations, and rigorous technical validation to encourage adoption by the research community. Well-suited applications must offer the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, cancer control, and/or epidemiology. Projects that are in-scope include technologies with new or significantly improved technical capabilities to measure, analyze, model, or interrogate cancer-related systems. These may include, but are not limited to, advanced molecular and cellular analysis platforms, multi-omic and spatial profiling methods, imaging and sensing technologies, immuno-engineering approaches, and innovations in biospecimen processing, modeling, and quality assessment. Technologies proposed for development may have potential for widespread applicability but must be focused in this proposal on cancer applications. Projects proposing application of existing technologies where the novelty resides in the clinical target or biological question being pursued are not appropriate for this solicitation. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.
Eligibility at a glance
- Eligible applicants
- Private institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Native American tribal governments (Federally recognized), City or township governments, County governments, For profit organizations other than small businesses, State governments, Public housing authorities/Indian housing authorities, Others (see text field entitled "Additional Information on Eligibility" for clarification), Public and State controlled institutions of higher education, Independent school districts, Native American tribal organizations (other than Federally recognized tribal governments), Special district governments, Small businesses, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Eligible locations
- Eligible applicants across the United States
- Eligible activities
- Health
- Matching requirement
- Not specified
- Registration
- SAM.gov, Grants.gov
Application process
- Read the complete official notice and confirm every eligibility rule.
- Complete required registrations early; federal registrations can take time.
- Build the budget, work plan, evidence, and attachments requested by the sponsor.
- Submit through the official portal and retain the confirmation.
Change history
No material changes have been recorded since this opportunity entered the hub.