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SC funding desk

Small business grants in South Carolina

South Carolina businesses can combine state and local programs with nationwide federal opportunities. This page separates direct business funding from research, export, intermediary, and support programs so owners can assess fit before applying.

Closer to home

South Carolina-specific opportunities

No approved state-specific listings in the current dataset

Check the official state source below and return after the next daily state-source sync.

Federal reach

Nationwide programs available in South Carolina

ROLLINGNationwide

Secretsos™ Small Business Grant

Secretsos

Secretsos™ Small Business Grant. The Secretsos™ Small Business Grant offers $2,500 quarterly to help entrepreneurs overcome challenges and accelerate growth. Designed for business owners who are often overlooked by traditional funding sources, the grant provides accessible support whether you’re jus

Award
Up to $2,500
Deadline
Rolling
Direct business grantSmall businessesDirect to business
source verifiedVerified Jul 28, 2026
ROLLINGNationwide

Awesome Foundation Grants

Awesomefoundation

Forwarding the interest of Awesome in the universe, $1,000 at a time.

Award
Up to $7,892,000
Deadline
Rolling
Direct business grantSmall businessesDirect to business
source verifiedVerified Jul 28, 2026
UNKNOWNNationwide

U.S. National Institutes of Health grants

Grants

U.S. National Institutes of Health grants. The U.S. National Institutes of Health (NIH) is currently funding grant opportunities related to COVID-19 research. These grants are reserved for small businesses that develop and research biomedical technology. There are multiple grants available with dead

Award
Amount not specified
Deadline
Not specified
CompetitionSmall businessesIntermediary / support
source verifiedVerified Jul 28, 2026
UNKNOWNNationwide

Innovation

Usa

Find ways you can participate through citizen science projects and challenges. Explore active competitions and volunteer opportunities. Innovation is essential to solving problems.

Award
Amount not specified
Deadline
Not specified
CompetitionApplicant type variesIntermediary / support
source verifiedVerified Jul 28, 2026
ROLLINGNationwide

Hey Helen Grant

Visionaries

Hey Helen Grant. The Hey Helen Grant, funded by Visionaries, offers $10,000 in unrestricted funding to support women and nonbinary entrepreneurs building mission-driven, for-profit businesses in the U.S. Eligible applicants must be 100% women-owned, generate less than $1 million in annual revenue, a

Award
Up to $1,000,000
Deadline
Rolling
CompetitionNonprofitsIntermediary / support
source verifiedVerified Jul 28, 2026
OPENNationwide

SEFSC Bluefin Tuna Research Program

Keisha Trent Grantor

The objective of the program is to provide a basis for advancing science-based fisheries management for Atlantic bluefin tuna. Such advancement will depend upon improvements in understanding of the fisheries, total abundance, and biology of bluefin tuna, especially regarding the effects of mixing an

Award
Up to $300,000
Deadline
Dec 31, 2026
Research grantNative American tribal governments (Federally recognized)Direct to business
source verifiedVerified Sep 2, 2026
UNKNOWNNationwide

Women-Owned Small Business Federal Contracting Program

Sba

Women-Owned Small Business Federal Contracting Program. The federal government seeks to award at least 5% of federal contracting dollars to women-owned small businesses annually. Through this SBA program, the Office of Women's Business Ownership provides support to women entrepreneurs by offering bu

Award
Up to $850,000
Deadline
Not specified
CompetitionSmall businessesIntermediary / support
source verifiedVerified Jul 28, 2026
ROLLINGNationwide

Verizon Small Business Digital Ready Program

Digitalready

Verizon Small Business Digital Ready Program. The Verizon Small Business Digital Ready Program offers free courses, events, networking, and other resources for small business owners, along with opportunities to receive grant funding. In partnership with LISC, Verizon is awarding $10,000 grants to 10

Award
Up to $10,000
Deadline
Rolling
Direct business grantSmall businessesDirect to business
source verifiedVerified Sep 3, 2026
ROLLINGNationwide

The Big Idea Grant

Small Business Grant for Women | We Empower Women Entrepreneurs to Succeed

The Big Idea Grant. The Big Idea Grant by Yippity Doo offers ambitious women entrepreneurs $1,000 to support their business ventures, along with access to mentorship, resources, and a wealth mindset coaching group. To qualify, applicants must be women entrepreneurs with a clear vision for their busi

Award
Up to $1,000
Deadline
Rolling
Training & supportSmall businessesIntermediary / support
source verifiedVerified Jul 28, 2026
OPENNationwide

NOI: PROSPECT Program: Providing Opportunities for Specialized Education in Critical Technologies

Golden Field Office

The U.S Department of Energy (DOE)’s Office of Critical Minerals and Energy Innovation (CMEI) intends to establish, on behalf of the Analysis and Strategy Office (ASO), the PROSPECT Program—Providing Opportunities for Specialized Education in Critical Technologies—and anticipates investing up to $10

Award
Up to $1
Deadline
Jan 15, 2027
Other fundingUnrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Intermediary / support
source verifiedVerified Aug 8, 2026
OPENNationwide

F26AS00105 National Fish Passage Program

Fish and Wildlife Service

The National Fish Passage Program (NFPP) provides technical and financial assistance to partners to remove instream barriers and restore aquatic connectivity, improve community safety, and support local economies. Fish passage projects benefit communities by reducing flood risk, improving recreation

Award
Up to $1,000,000
Deadline
Apr 30, 2027
Other fundingUnrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Intermediary / support
source verifiedVerified Aug 25, 2026
OPENNationwide

Innovative Traffic Safety Enforcement (ITSE) Grant Program

Anoko A Zankli Grantor

The primary intent of this of the ITSE Grant Program is to 1) develop innovative traffic safety enforcement programs that demonstrate effectiveness by reducing the number of motor vehicle crashes due to one or more of the subject risky driving behaviors; and 2) ensure the traffic safety enforcement

Award
Up to $20,000,000
Deadline
Sep 1, 2027
Other fundingUnrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Intermediary / support
source verifiedVerified Aug 4, 2026

Applying for grants in South Carolina

Does forming an LLC make a business eligible?

No. Entity type is only one possible requirement. Review size, ownership, location, activity, registration, and deadline rules in the official notice.

Are nationwide grants copied into each state?

No. A nationwide opportunity has one canonical record and appears here because eligible South Carolina businesses may be able to apply.

Where should I verify a deadline?

Always use the official source and application portal linked on the opportunity page. Our verification date tells you when the listing was last checked.

Read application guides